How, then, do we explain the fact that it helps people with chronic Lyme disease feel better? — My ambitious and once-athletic wife has wrestled with chronic Lyme disease for her entire adult life. She has contended with unrelenting muscle stiffness, extreme chest pain, numbness in face, hands and feet, eye twitching, difficulty writing, speaking and forming words, memory loss, brain fog, incontinence, sinus and dental pain.